Home » Prescription Drugs 8 » GASTRACTIV Vivadone
This medicine contains the active ingredient domperidone which is a type of medicine called a dopamine antagonist. It is an anti-emetic medicine meaning it is used to treat nausea and vomiting. It can also be used to treat abdominal bloating fullness and discomfort in adults.Domperidone works primarily by blocking dopamine receptors found in an area of the brain known as the chemoreceptor trigger zone (CTZ). The CTZ is activated by nerve messages from the stomach when an irritant is present. It is also activated directly by agents circulating in the blood for example anti-cancer medicines. Once activated it sends messages to another area of the brain the vomiting centre which in turn sends messages to the gut causing the vomiting reflex. Blocking the dopamine receptors in the CTZ prevents nausea messages from being sent to the vomiting centre. This reduces the sensation of nausea and prevents vomiting. Domperidone also blocks dopamine receptors found in the upper end of the digestive system. This results in tightening of the muscles at the entry to the stomach relaxation of the muscles at the exit of the stomach and increased contraction of the muscles in the stomach itself. These actions speed the passage of food through the stomach into the intestine which physically helps to prevent vomiting. Both actions make domperidone useful in treating nausea and vomiting due to many causes including anti-cancer chemotherapy emergency hormonal contraception and in migraine. Domperidone is also used to prevent nausea and vomiting that can be caused by medicines for Parkinson's disease such as levodopa bromocriptine and apomorphine.Due to its stimulating action on the gut which speeds up stomach emptying into the intestine domperidone can also be used to relieve upper abdominal discomfort a sense of fullness or bloating and regurgitation of the stomach contents that some people experience following meals. (Domperidone can be bought over-the-counter from pharmacies for the relief of after meal symptoms as the branded product Motilium 10. For more information ask your pharmacist. The non-prescription Motilium 10 product is not suitable for use by children under 16 years of age.)What is it used for?Nausea and vomiting in adults and childrenRelief of upper abdominal discomfort sense of fullness and regurgitation of stomach contents in adults
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About GASTRACTIV Vivadone:
Product Type: Prescription Drugs 8
GASTRACTIV ( Vivadone Generic Domperidone )
GASTRACTIV (Vivadone Generic Domperidone)
Vivadone Generic Domperidone
10mg 200 (20 x 10)
Vivadone Generic Domperidone GASTRACTIV

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Prescription Drugs 8
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World Drug News. Government funding crisis in Swaziland disrupts supply of HIV/AIDS supplies. "An acute government funding crisis in Swaziland, Africa's last absolute monarchy, is disrupting supplies of HIV/AIDS drugs and hampering the fight against the virus in the country with the world's highest infection rate, Medecins Sans Frontieres (MSF) said Friday," Reuters reports. "Stocks of testing kits and related chemicals were 'almost dry,' making it next-to-impossible to chart the progress of the 70,000 patients on therapy or more than 130,000 other people carrying the virus, the aid agency said," according to Reuters.
"With 26 percent of its adult population, or more than 200,000 people infected, Swaziland ranks as the most AIDS-affected country," Reuters writes (Cropley, (9/9). In related news, a new report from Swaziland's government "has found that more than half of [30,000 Swazis, mostly women, working] in Swaziland's garment industry are living with HIV, and officials are realizing that the once-hailed promise of manufacturing employment has become a financial and medical nightmare for tens of thousands of Swazi women," PlusNews reports (8/11).
This article was reprinted from kaiserhealthnews.org with permission from the Henry J. Kaiser Family Foundation. Kaiser Health News, an editorially independent news service, is a program of the Kaiser Family Foundation, a nonpartisan health care policy research organization unaffiliated with Kaiser Permanente.
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